7 May 2021
Uncomplicated urinary tract infections (uUTI) are responsible for a high proportion of antibiotic prescriptions in primary care. In general, the development of treatment approaches to reduce the consumption of antibiotics represents a global challenge. For uUTI, different approaches to reduce antibiotic consumption have been tested in randomized controlled trials. The meta-analytical evaluation of these studies represents a promising approach to compare these strategies and to identify predictors of non-antibiotic therapy success.
The symposium “Management of UTI in clinical practice: How to achieve the best use of evidence?” will present and discuss methodological peculiarities and challenges as well as new findings in diagnostics and therapy.
08:45 a.m.: Greetings and Introduction - Ildikó Gágyor (Würzburg), Tim Friede (Göttingen)
Session 1: Clinical background on UTI, antibiotics and resistance (Chair: Eva Hummers, Andreas Kronenberg)
09:00 a.m.: Keynote Lecture (Paul Little, Southampton)
'Tackling antibiotic resistance in primary care: What antibiotic stewardship interventions work?'
09:30 a.m.: Presentation 1 (Virginia Hernandez, St. Andrews)
'Primary care antimicrobial stewardship: can it make an impact on antimicrobial resistance?'
09:45 a.m.: Presentation 2 (Ronny Gunnarsson, Göteborg)
'Estimating the probability for a link between a bacterial finding and a specific symptom in the absence of a gold standard'
10:00 a.m.: Presentation 3 (Stefan Heytens, Ghent)
'AB susceptibility surveillance of cystitis in primary care'
10:15 - 10:30 a.m.: MOVING BREAK - Desk-friendly workout (Andreas Petko, Würzburg)
10:30 - 10:45 a.m.: BREAK
Session 2: Evidence synthesis - Challenges ind insights of meta-analyses (Chair: Beth Stuart, Stefan Heytens)
10:45 a.m.: Keynote Lecture (Sofia Dias, York)
'Evidence synthesis for decision making: multiple treatments, multiple outcomes'
11:15 a.m.: Presentation 4 (Thomas Debray, Utrecht)
'Prediction of absolute treatment benefit: challenges and opportunities'
11:40 a.m.: Presentation 5 (Yvonne Kaußner, Würzburg and Christian Röver, Göttingen)
'Strategies to reduce antibiotics in treating uncomplicated urinary tract infections - a systematic review and meta-analysis of individual patient data'
12:00 - 01:00 p.m.: BREAK
Session 3: Clinical Outlook - Different populations, diagnostics and treatment of UTI (Chair: Alastair Hay, Ingvild Vik)
01:00 p.m.: Presentation 6 (Akke Vellinga, Galway)
'UTI in men - a review of the literature'
01:15 p.m.: Presentation 7 (Anne Holm, Kopenhagen)
'UTI in nursing homes - navigating complexity'
01:30 p.m.: Presentation 8 (Kome Gbinigie, Oxford)
'Can cranberry treat UTIs? The CUTI study'
01:45 p.m.: Presentation 9 (Florian Wagenlehner, Gießen)
'Acute Cystitis Symptom Score (ACSS) for diagnostics and patient reported outcome in patients with acute uncomplicated cystitis'
02:00 p.m.: Presentation 10 (Hannes Ullrich, Berlin/ Kopenhagen)
'Using register-based data to understand physician decision-making: machine learning predictions and an economic model'
02:15 p.m.: Closing words (Ildikó Gágyor, Würzburg and Tim Friede, Göttingen)
This schedule is subject to minor changes.